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Biology Department

David Domozych

David Domozych

Professor of Biology in the Department of Biology
Director of the Skidmore Microscopy Imaging Center


Dana Science Center, Office # 339B 

Biology Department

Skidmore College

Saratoga Springs, NY 12866


(518) 580-5075


(518) 580-5071



Other Positions Held:

2011, Visiting Scientist, National University of Ireland, Galway.

1989-1990, Visiting Scientist, John Innes Institute, Norwich England. 

1997-1998, Visiting Professor, Section of Plant Biology, Cornell University.

Courses Taught at Skidmore:

Plant Biology (BI 237)

Biological Electron Microscopy (BI 311)

Plant Biochemistry and Physiology (BI 337)

Plant Biotechnology (BI 338)

Advanced Light Microscopy (BI 362)

Research Interests:

David Domozych is a plant cell biologist who studies the evolution of cell walls and their biosynthesis in plants. He is interested in the biochemistry and cell biology of cell wall components (esp. pectins) in the Charophycean Green Algae (CGA), the modern group of green algae whose ancestors are the basal stock from which land plants evolved. Dr. Domozych's primary research tools include light, confocal laser scanning and electron microscopy, various biochemical techniques and immunocytochemistry. His main subject of study is a new model organism, Penium margaritaceum, a unicellular desmid with cell polymers similar to those of higher plants. Currently, his research work is involved with answering questions like:

Dr. Domozych's work has recently been sponsored by grants from the National Science Foundation's (NSF) Molecular and Cell Biology Program, NSF Intergrated Organismal Systems and NSF Major Instrumentation Programs. Many students participate in his research program both during the academic year and summer.

Recent Publications:

Rydahl, M. G., Fangel, J. U., Mikkelsen, M. D., Johansen, I. E., Andreas, A., Harholt, J., Ulvskov, P., Jørgensen, B., Domozych, D. S. and Willats, W. G. T. (2015) Penium margaritaceum as a Model Organism for Cell Wall Analysis of Expanding Plant Cells. In: Plant Cell Expansion. Methods in Molecular Biology Volume 1242 (ed. Estevez, J); Springer, New York, pp 1-23.

Worden, N., Esteve, V., Domozych, D. S. and Drakakaki, G. (2015) Using Chemical Genomics to Study Cell Wall Formation and Cell Growth in Arabidopsis thaliana and Penium margaritaceum. In: Plant Cell Expansion. Methods in Molecular Biology Volume 1242 (ed. Estevez, J); Springer, New York, pp 23-39.

Domozych, D. S. Sørensen, I., Popper, Z. A., Ochs, J., Andreas, A., Fangel, J. U., Pielach, A., Sacks, C., Brechka, H., Willats, W. G. T. and Rose, J. K. C. (2014) Pectin metabolism and assembly in the cell gall of the Charophyte Green alga Penium margaritaceum. Plant Physiology 165: 105-118.

Domozych, D. S. and Domozych, C. E. (2014) Multicellularity in green algae: upsizing in a walled complex. Frontiers in Plant Science (doi: 10.3389/pls.2014).

Domozych, D. S. (2014) Penium margaritaceum: a unicellular model organism for studying plant cell wall architecture and dynamics" Plants 3: 543-558.

Domozych, D. S., Sørensen, I., Sacks, C., Brechka, H., Andreas, A., Fangel, J. U., Rose, J. K. C. Willats, W. G. T. and Popper, Z. A. (2014) Disruption of the microtubule network alters cellulose deposition and causes major changes in pectin distribution in the cell wall of the green alga, Penium margaritaceum. Journal of Experimental Botany 65: 465-479.

Domozych, D. S. (2014) Cell wall evolution and diversity. In: Polysaccharides: Bioactivity and Biotechnology (Ramawat, K. and Merillon, J. M., eds) Springer, NY, pp. 1-23.

Ochs, J., LaRue, T., Tinaz, B., Yongue, C. and Domozych, D. S. (2014) The cortical cytoskeletal network and cell-wall dynamics in the unicellular charophycean green alga Penium margaritaceum. Annals of Botany 114: 11237-1250.

Larson, E. R., Domozych, D. S. and Tierney, M. L. (2014) SNARE VTI13 plays a unique role in endosomal trafficking pathways with the vacuole and is essential for cell wall organization and root hair growth in Arabidopsis. Annals of Botany 114: 11147-1150.

Larson, E. R., Tierney, M. L., Tinaz, B. and Domozych, D. S. (2014) Using monoclonal antibodies to label living root hairs: a novel tool for studying cell wall microarchitecture and dynamics in Arabidopsis. Plant Methods 2014, 10:30

Popper, Z. A., Ralet, M.-C. and Domozych, D.S. (2014) Plant and algal cell walls: diversity and functionality. Annals of Botany 114: 1043-1048.

Pielach, A., Leroux, O., Domozych, D.S., Knox, J.P. and Popper, Z. A. (2014) Arabinogalactan protein-rich cell walls, paramural deposits and ergastic globules define the hyaline bodies of rhinanthoid Orobanchaceae haustoria. Annals of Botany 114: 1359-1376.

Mravec, J., J., Kračun, S.K., Rydahl, M.G., Westereng, B., Miart, F., Clausen, M.H., Fangel, J.U., Daugaard, M., Van Cutsem, P., De Fine Licht, H.H., Höfte, H., Malinovsky, F.G., Domozych, D.S. and Willats, W.G.T. (2014) Tracking developmentally regulated post-synthetic processing of homogalacturonan and chitin using reciprocal oligosaccharide probes. Development 141: 4841-4850

Sørensen, I., Fei, Z., Andreas, A., Willats, W.G.T., Domozych, D.S. and Rose, J.K.C. (2013) Stable Transformation and Reverse Genetic Analysis of Penium margaritaceum: A Platform for Studies of Charophycean Green Algae, the Immediate Ancestors of Land Plants. The Plant Journal 77: 339–351

Domozych, D.S., Fujimoto, C. and LaRue T. (2013) Polar Expansion Dynamics in the Plant Kingdom: A Diverse and Multifunctional Journey on the Path to Pollen Tubes. Plants 2: 148-173.

Buda, G.J., Barnes, W.J., Fich, E.A., Park, S. Yeats, T.H., Zhao, L., Domozych, D.S. and Rose, J.K.C. (2013) An ATP Binding Cassette Transporter Is Required for Cuticular Wax Deposition and Desiccation Tolerance in the Moss Physcomitrella patens. Plant Cell 25: 4000-4013.

Ulvskov, P., Paiva, D.S., Domozych, D.S. and Harholt, J. (2013) Classification, naming and evolutionary history of glycosyltransferases from sequenced red and green algal genomes. PLOS ONE doi: 10.1371/journal.pone.0076511

Domozych, D.S., Ciancia, M., Fangel, J. U., Mikkelsen, M.D., Ulvskov, P. and Willats, W. G. T. (2012) The cell walls of green algae: a journey through evolution and diversity. Frontiers in Plant Physiology doi: 10.3389/fpls.2012.00082.

Domozych, D.S. (2012) The quest for four-dimensional imaging in plant cell biology: it’s just a matter of time. Annals of Botany 110: 461-474.

Yeats, T.H., Martin, L.B., Viart, H., Isaacson, T., He, Y., Zhao, L., Matas, A.J., Buda, G.J., Domozych, D.S., Clausen, M.H. and Rose, J.K.C. (2012) The identification of cutin synthase: formation of the plant polyester cutin. Nature Chemical Biology doi:10.1038/nchembio.960

Sørensen, I., Rose, J.K.C., Doyle, J. J., Domozych, D.S., and Willats, W.G.T. (2012). The Charophycean green algae as model systems to study plant cell walls and other evolutionary adaptations that gave rise to land plant. Plant Signaling and Behavior 7: 1–3.

Sørensen, I., Pettolino, F., Bacic, A., Ralph J., Lu, F., O'Neill, M., Fei, Z. Rose, J.K.C., Domozych, D.S. and Willats, W.G.T. (2011) The Charophycean green algae provide insights into the early origins of plant cell walls. Plant Journal 68, 201-211.

Popper, Z.A., Michel, G., Hervé, C., Domozych, D.S., Willats, W.G.T., Tuohy, M.G., Kloareg, B. and Stengel, D.B. (2011) Evolution and Diversity of Plant Cell Walls: From Algae to Flowering Plants. Annual Review of Plant Biology 62, 567-590.

Grants received:-Last 5 years

NSF MRI 1337280: Acquisition of a confocal laser scanning microscope for research in the life sciences at Skidmore College; 09/01/2013-08/31/2016; $478,730.00.

NSF MCB 1009978: The cell biology of pectin dynamics in the Charophycean Green Algae: Homogalacturonan secretion in the model organism, Penium margaritaceum; 02/10/2010-09/30/2012; $232,000.

NSF MRI 0922805: MRI: Acquisition of a Libra 120 transmission electron microscope for research enhancement at Skidmore College. 01/01/2010- 12/31/2013; $721,046.00.

NSF MRI 0959476: MRI-R2: From Molecules to Ecosystems: Establishment of the Skidmore Analytical Interdisciplinary Laboratory (SAIL); 01/01/2010- 12/31/2014; $557,755.00.

NSF IOS: 0848071: Evolution of the Land Plant Cell Wall: Functional Significance of Land Plant Polymers within the Charophycean Green Algae; 07/15/2009-07/01/2012; $131,000.

Research Collaborators from around the world:

Dr. Zoe Popper, National University of Ireland
Drs. Jocelyn Rose and Iben Sorensen, Cornell University
Dr. William Willats, University of Copenhagen
Dr, Georgia Drakakaki, University of California at Davis
Dr. Mary Tierney, University of Vermont