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$900K NIH
Grant to Support Estrogen Research
Assistant
Professor of Biology Marc J. Tetels research on the action
of estrogen in the brain has garnered $892,000 in funding from the
National Institutes of Health (NIH), through its National Institute
of Diabetes and Digestive and Kidney Diseases. Funding has been
awarded to Tetel and Skidmore for four years, beginning with $219,000
in the academic year 2002-03.
This is wonderful news, and needless to
say, important work, said Interim Vice President for Academic
Affairs and Dean of the Faculty Charles Joseph, adding that it is
work such as Tetels that helps Skidmore continue to develop
an enviable reputation as a research institution.
Tetel studies ovarian steroid hormones, estradiol
and progesterone, particularly the way in which they act in the
brain to regulate gene expression and female reproductive behavior.
His research will focus on how estrogen interacts with its receptor
and other proteins, known as nuclear receptor coactivators, to activate
specific genes in the brain. Results of his research, begun with
an earlier grant of $100,000 from NIH and the Office of Research
for Womens Health, have implications for hormone-influenced
diseases and disorders, including depression and breast cancer.
The grant will support research equipment, supplies,
and personnel a full-time technician, three student research
assistants, and possibly a postdoctoral researcher as well. In the
mode of Skidmore collaborative research, each student will have
an independent project. About 20 percent of the grant will go to
the College in support of Tetels research.
Tetel joined the College as assistant professor
of biology in 2001, concurrent with the start of a new major in
neurosciences. I was looking for a school that valued teaching
and research, in a liberal arts environment with bright students,
says Tetel, who says he was also drawn to the college by the
way Skidmore is supporting and developing the sciences. He
teaches an introductory course in neuroscience and an advanced course
in neuroendocrinology, in addition to serving as part of the faculty
team for Liberal Studies 1, the course taken by all first-year Skidmore
students.
A graduate of Northwestern University,
where he earned a B.A. in biological sciences, Tetel earned a Ph.D.
in neurosciences and behavior at the University of Massachusetts
at Amherst. Prior to coming to Skidmore, he did postdoctorate work
in molecular endocrinology at the University of Colorado Health
Sciences Center and was visiting assistant professor at the University
of Massachusetts, Amherst. His work has been
published in the Journal of Neuroendocrinology, Molecular Endocrinology,
Endocrinology, and the Proceedings of the National Academy of Sciences.
Photo above: Marc Tetel and research assistant Cheryl Jenks,
a 1999 Skidmore graduate, share a light moment in the lab.
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