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Skidmore College
Health and Human Physiological Sciences

Robert RestainoRobert Restaino

Visiting Assistant Professor for Health and Human Physiological Sciences Department

Phone:  518-580-8379
Fax:   518-580-8356
Email:  rrestain@skidmore.edu
Location:  Sports and Recreation Center Office 239

Education:

  • BS in Biology, Niagara University, 2010
  • MS in Biology, Eastern New Mexico University, 2013
  • Clinical Research, University of Missouri, 2013-2018

Courses Taught:

  • HP 111 Introduction to Exercise Physiology
  • HP 111 Introduction to Exercise Physiology Laboratory
  • HP 126 Human Anatomy and Physiology I Laboratory

Current Research Interests:

My research interests lie primarily in human vascular function and blood flow regulation as it is altered in cases of obesity, metabolic syndrome, and type 2 diabetes. The inflammatory state induced in the setting of cardiometabolic disease can lead to vascular dysfunction mediated by increased central sympathetic outflow, impairment in endothelial mediated vasorelaxation, or immunological interactions between the vascular walls and circulating leukocytes. I approach study of these physiological phenomena in a translational fashion utilizing cell culture based basic science and combining this with clinical studies in patient populations. My goal in this body of work is to parallel human based research with mechanistic science in order to describe what truly occurs in vivo.

Publications:

  • Seth W. Holwerda, Robert M. Restaino, Paul J. Fadel; Adrenergic and Non-Adrenergic Control of Active Skeletal Muscle Blood Flow: Implications for Blood Pressure Regulation During Exercise; Autonomic Neuroscience 2014 (Review)
  • Robert M. Restaino, Seth W. Holwerda, Daniel P. Credeur, Paul J. Fadel, Jaume Padilla; Impact of Prolonged Sitting on Lower and Upper Limb Micro- and Macrovascular Function; Experimental Physiology 2015
  • Daniel P. Credeur, Seth W. Holwerda, Robert M. Restaino, Philip M. King, Kiera L. Crutcher, M. Harold Laughlin, Jaume Padilla, Paul J. Fadel; Characterizing Rapid-Onset Vasodilation to Single Muscle Contractions in the Human Leg; Journal of Applied Physiology 2015
  • Seth W. Holwerda, Leryn J. Reynolds, Robert M. Restaino, Daniel P. Credeur, Heather J. Leidy, John P. Thyfault, Paul J. Fadel; The Influence of Reduced Insulin Sensitivity via Short-Term Reductions in Physical Activity on Cardiac Baroreflex Sensitivity During Acute Hyperglycemia; Journal of Applied Physiology 2015
  • Seth W. Holwerda, Robert M. Restaino, Camila Manrique Acevedo, Guido Lastra, James P. Fisher, Paul J. Fadel; Augmented Pressor and Sympathetic Responses to Skeletal Muscle Metaboreflex Activation in Type 2 Diabetes; American Journal of Physiology-Heart and Circulatory Physiology 2015
  • Robert M. Restaino, Lauren K. Walsh, Takuma Morishima, Jennifer R. Vranish, Luis A. Martinez-Lemus, Paul J. Fadel, Jaume Padilla; Endothelial Dysfunction Following Prolonged Sitting is Mediated by a Reduction in Shear Stress; American Journal of Physiology-Heart and Circulatory Physiology 2016
    *Highlighted for podcast*
  • Takuma Morishima, Robert M. Restaino, Lauren K. Walsh, Jill A. Kanaley, Paul J. Fadel, Jaume Padilla; Prolonged Sitting-Induced Leg Endothelial Dysfunction is Prevented by Fidgeting; American Journal of Physiology-Heart and Circulatory Physiology 2016
  • Lauren K. Walsh, Robert M. Restaino, Martha Neuringer, Camila Manrique, Jaume Padilla; Administration of Tauroursodeoxycholic Acid prevents Endothelial Dysfunction caused by an Oral Glucose Load; Clinical Science 2016
  • Seth W. Holwerda, Lauro C. Vianna, Robert M. Restaino, Kunal Chaudhary, Colin N. Young, Paul J. Fadel; Arterial Baroreflex Control of Sympathetic Nerve Activity and Heart Rate in Patients with Type 2 Diabetes; American Journal of Physiology-Heart and Circulatory Physiology 2016
  • Robert M. Restaino, Shekhar H. Deo, Alan R. Parrish, Paul J. Fadel, Jaume Padilla; Increased Monocyte Derived Reactive Oxygen Species in Type 2 Diabetes: Role of Endoplasmic Reticulum Stress; Experimental Physiology 2017
  • Takuma Morishima, Robert M. Restaino, Lauren K. Walsh, Jill A. Kanaley, Jaume Padilla; Prior Exercise and Standing as Strategies to Circumvent Sitting-Induced Leg Endothelial Dysfunction; Clinical Science 2017
  • Lauren K. Walsh, Robert M. Restaino, Luis A. Martinez-Lemus, Jaume Padilla; Prolonged Leg Bending Impairs Endothelial Function in the Popliteal Artery; Physiological Reports 2017