12
Turning pliés into gargoyles: Mental rehearsal strategy and choreography retention
-
Sarah A. Green ’16
- Linh K.
Hoang ’16
Snoezelen: Examining a multisensory approach to improving cognitive performance and
coping with stress
- Daphne M. Preti ’16
Reducing gender identity bias through imagined intergroup contact
- Helena Rabasco ’16
The effect of mortality salience and motivational orientation on attitudes toward work
-
Yoon Young Sim ’16
The processing of blend words: An eye-tracking study
- Sarah Rose Slate ’16
The preferred viewing position in top to bottom sentence reading
- Emma Starr ’16
B.
Thesis Research in Neuroscience
(TLC 100)
Cerebellar mitochondrial deficits in SCA1: targeting a potential treatment
Faculty Sponsor: Jennifer Bonner, Neuroscience
Neuroscience Presenters: Evan Marzouk ’16, Monica Villegas ’16, Jenny Zhang ’16
Spinocerebellar Ataxia Type 1 (SCA1) is a neurodegenerative disease that currently has
no treatment. Using SCA1 cell and mice models, we posit mitochondrial deficits may
exacerbate disease progression. Our results suggest dysfunctional OXPHOS respiration
and morphological deficits in the mitochondria. Chronic succinic acid treatment of SCA1
mice improves balance and motor learning and restores Purkinje somatic and dendritic
viability. Our work presents mitochondrial intervention as a potential therapy for slowing
SCA1 disease progression.
The Role of 5-HT
1A
and 5-HT
2A
in the Anticonvulsant Effect of Cannabidiol
-
Kate
Schoolcraft ’16
Cannabidiol (CBD) is a non-psychoactive compound found in the
Cannabis
plant that has
potential anti-convulsant efficacy. The mechanism by which CBD produces these effects
is unknown. This study investigated the role of two serotonergic receptors, the 5-HT
1A
and 5-HT
2A
, in mediating CBD’s anti-seizure effects using an acute seizure rodent
model.
Morphometric analysis of zebrafish embryos
-
Timothy Lehmberg ’16
Using these 2D and 3D models for Place Component Analysis, we demonstrate their
application in determining the percent contribution of an environmental or genetic factor
on the total neuromorphology of the developing system by mathematically defining the
geometry of the neurons. We also report the findings of a pilot study investing the
development of 4D morphometrics and its application to spatially defining the pathway
of a developing nervous system.
Concussion and Olfactory Deficits in Undergraduate students
-
Zoe E. Brasher ’16,
