Fall
Term 2004, Skidmore College
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| Date | *Reading Assignment | Important reminders/Topics | ||
| Th 9/9 | chapter 1 | Introduction and overview | ||
| Tu 9/14 | chapter 1 | Introduction and overview | ||
| Th 9/16 | No Class, Rosh Hashonah | |||
| Tu 9/21 | chapter 2 | Antibody structure and diversity | ||
| Th 9/23 | chapter 2 | Antibody structure and diversity | ||
| Tu 9/28 | research paper | Term
project topic choice is due at 11:10 in class. Hozumi and Tonegawa: Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions. |
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| Th 9/30 | chapter 3 |
Quiz #1 |
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| Tu 10/5 | chapter 3 | Antigen recognition by T lymphocytes | ||
| Th 10/7 | chapter 4 | Antigen
recognition by T lymphocytes
MHC restriction worksheet |
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| Tu 10/12 | chapter 5 | Development of B lymphocytes | ||
| Th 10/14 | Term
project bibliography, outline, and worksheet are due at 11:10 in class. Case study Development of T lymphocytes |
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| Tu 10/19 | research paper | Liu, Y. and Janeway, C.A.: Cells that present both specific ligand and costimulatory activity are the most efficient inducers of clonal expansion of normal CD4 T cells. PNAS 89: 3845-3849, 1992. | ||
| Th 10/21 | Exam #1 | |||
| Tu 10/26 | WEB WORKSHOP: Meet in Harder 101 | |||
| Th 10/28 | research paper | Liu, Y. and Janeway, C.A.: Cells that present both specific ligand and costimulatory activity are the most efficient inducers of clonal expansion of normal CD4 T cells. PNAS 89: 3845-3849, 1992. | ||
| Tu 11/2 | chapter 6 |
Activation of T lymphocytes |
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| Th 11/4 | chapter
7 |
Activation of B lymphocytes | ||
| Tu 11/9 | research paper | First
draft of term project is due at 11:10 in class. Gearhart, P.J.: The roots of antibody diversity. Nature 419: 29-30, 2002. |
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| Th 11/11 | chapter 8 | Quiz
#2 Defense against infection |
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| Tu 11/16 | chapter 8 | Defense against infection | ||
| Th 11/18 | chapter 9 | Failure of the body's defenses | ||
| Tu 11/23 | Student presentations of term projects |
A.Klein,
N.Temin: Type I Diabetes |
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| Tu 11/30 | Student presentations of term projects |
Z.Toth,
J.Yamauchi: Hodgkins'
Lymphoma |
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| Th 12/2 | Student presentations of term projects | C.Campo,
L.Wolfe, N.Sparbeck: Hashimoto's
Thyroiditis J.Leati, E.McElhenny: Lupus erythematosus A.Bennett, J.Boulais: Rheumatoid arthritis |
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| Tu 12/7 | chapter 12 | Term
project is due at 11:10 in class. Immunization |
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| Th 12/9 | research paper | V.Verez-Bencomo et al.: A synthetic conjugate polysaccharide vaccine against haemophilus influenzae type b. Science 305: 522-525, (July) 2004 | ||
| Tu 12/14 | handout | Evolution of Immune Mechanisms | ||
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