77:  Marries Terentia.  They have two children, a daughter Tullia (born c. 79) and a son Marcus (b. 65).  Marcus, though not as famous as his father, attained distinction as an officer and as consul in 30.

46:  His marriage becomes loveless and he divorces Terentia.  He then remarries his young ward, Publilia.

45:  Tullia dies shortly after bearing a son (her marriage to Dolabella, the father, had ended late the previous year) to the incredible grief of Cicero.  He retreats to his villa in Tuscany in woeful solitude.  He also divorces Publilia, whom he accused of not caring enough about the girl's death.

7 December 43:   Antony, angered by Cicero's attacks on him in the Phillipics , sends assassins to murder Cicero at Formiae, on the coast south of Rome; he faced death bravely, as Plutarch relates , "he looked steadfastly upon his murderers, his person covered with dust, his beard and hair untrimmed, and his face worn with his troubles....stretching forth his neck out of the litter." In the same year, Quintus and his son also fall victim to the proscriptions of the Second Triumvirate.