| CONTACT INFO
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STANDARD MAIL
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| Department of Chemistry
Skidmore College
815 North Broadway
Saratoga Springs
New York, 12866-1632 |
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Department PHONE
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| 518-580-5120 |
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518-580-5139
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Michelle
W. Frey
Assistant Professor of Chemistry
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Office: Dana 223
Phone: 518-580-5135
Fax: 518-580-5139
mfrey@skidmore.edu |
B.A. 1989, Ithaca College
Ph.D. 1995, The Pennsylvania State University
Post-doctoral Researcher 1995-1996, DuPont Merck Pharmaceutical
Company
At Skidmore since 2002
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Research
My research group’s interests focus upon the mechanistic
enzymology of metal-containing hydrolases. In particular, we are
interested in the mechanisms by which metalloproteases cleave
peptide bonds. We are currently studying a novel aminopeptidase
from the marine bacterium Vibrio fischeri. We believe
that this enzyme is involved in the establishment of the symbiotic
relationship between the bacterium and its host, the sepiolid
squid Euprymna scolopes. The symbiotic association between
V. fischeri and E. scolopes is an excellent
model system for the study of both benign and pathogenic bacteria-host
interactions. A more complete understanding of the intricacies
of these relationships and their establishment is necessary for
the development of novel therapeutic strategies.
Courses
CH 103 Fundamentals of Chemistry
CH 105 Chemical Principles I
CH 106 Chemical Principles II
CH 341 Biochemistry: Macromolecular Structure and Function
CH 342 Biochemistry: Intermediary Metabolism
Creative Thought Matters.
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