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Skidmore College
Skidmore Analytical Interdisciplinary Laboratory (SAIL)

Liquid chromatograph-mass spectrometer (LC-MS)

liquid chromatograph-mass spectrometer

The Thermo Vanquish liquid chromatograph with ISQ-EC mass spectrometer is ideal for analysis of small molecules in solution.  Compounds in the sample are separated as they pass through the liquid chromatography column.  As each compound reaches the detector, it produces a mass spectrum, by which it can be identified.


  • Quaternary pump
  • Auto-sampler injection
  • Temperature-controlled sampler and column compartments
  • Isocratic and gradient separations
  • UV-Vis detector monitors up to 4 wavelengths simultaneously
  • Charged aerosol detector (CAD) for analytes that are not easily detectable by UV-Vis and mass spectrometry

Available columns

  • Restek Ultra C18 5-micron 100 x 4.6 mm
  • Restek Ultra C18 5-micron 150 x 4.6 mm
  • Restek Ultra AQ C18 5-micron 150 x 4.6 mm