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Skidmore College
Biology Department
Jason Breves

Jason Breves

Associate Professor AND CHAIR

Address:
Department of Biology - CIS 110H
Skidmore College
Saratoga Springs, NY 12866

Laboratory webpage

Telephone: (518) 580-5079
Fax: (518) 580-5071
E-mail: jbreves@skidmore.edu

Education:

  • B.S., Roger Williams University (Marine Biology)
  • M.S., University of Rhode Island (Oceanography)
  • Ph.D., University of Hawaii (Molecular Biosciences and Bioengineering)
  • Postdoctoral Studies, University of Massachusetts Amherst

Courses:

  • Human Dilemmas (SSP 100)
  • Comparative Vertebrate Physiology (BI 244)
  • Mammalian Physiology (BI 306)
  • Endocrinology (BI 343)
  • Aquatic Animal Physiology (BI 351)

Current Support:

Recent Publications:

  • Celino-Brady FT, Breves JP, Seale AP.Sex-specific responses to growth hormone and luteinizing hormone in a model teleost, the Mozambique tilapia. General and Comparative Endocrinology 329: 114119.
  • Breves JP, McKay IS, Koltenyuk V, Nelson NN, Lema SC, McCormick SD. 2022. Na+/HCO3- cotransporter 1 (nbce1) isoform gene expression during smoltification and seawater acclimation of Atlantic salmon. Journal of Comparative Physiology B 192: 577-592. 
  • Seale AP, Breves JP. 2022. Endocrine and osmoregulatory responses to tidally-changing salinities in fishes. General and Comparative Endocrinology 326: 114071. 
  • Breves JP, Puterbaugh KM, Bradley SE, Hageman AE, Verspyck AJ, Shaw LH, Danielson EC, Hou Y. 2022. Molecular targets of prolactin in mummichogs (Fundulus heteroclitus): ion transporters/channels, aquaporins, and claudins. General and Comparative Endocrinology 325: 114051. 
  • Woo DW, Malintha GHT, Celino-Brady FT, Yamaguchi Y, Breves JP, Seale AP. 2022. Tilapia prolactin cells are thermosensitive osmoreceptors. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 322: R609-R619. 
  • Seale LA, Gilman CL, Zavacki AM, Larsen PR, Inokuchi M, Breves JP, Seale AP. 2021. Regulation of thyroid hormones and branchial iodothyronine deiodinases during freshwater acclimation in tilapia. Molecular and Cellular Endocrinology 538: 111450.
  • Breves JP, Nelson, NN, Koltenyuk V, Petro-Sakuma CK, Celino-Brady FT, Seale AP. 2021. Enhanced expression of ncc1 and clc2c in the kidney and urinary bladder accompanies freshwater acclimation in Mozambique tilapia. Comparative Biochemistry and Physiology, Part A 260: 111021.
  • Shaughnessy CA, Breves JP. 2021. Molecular mechanisms of Cl- transport in fishes: new insights and their evolutionary context. Journal of Experimental Zoology A 335: 207-216.
  • Seale AP, Malintha T, Celino-Brady FT, Belcaid M, Yamaguchi Y, Lerner DT, Baltzegar DA, Borski RJ, Head T, Stoytcheva ZR, Breves JP. 2020. Transcriptional regulation of prolactin in a euryhaline teleost: characterization of gene promoters through in silico and transcriptomic analyses. Journal of Neuroendocrinology 32: e12905.  
  • Breves JP, Popp EE, Rothenberg EF, Rosenstein CW, Maffett KM, Guertin RR. 2020. Osmoregulatory actions of prolactin in the gastrointestinal tract of fishes. General and Comparative Endocrinology 298: 113589.
  • Breves JP, Springer-Miller RH, Chenoweth DA, Paskavitz AL, Chang AYH, Regish AM, Einarsdottir IE, Björnsson BT, McCormick SD. 2020. Cortisol regulates insulin-like growth-factor binding protein (igfbp) gene expression in Atlantic salmon parr. Molecular and Cellular Endocrinology 518: 110989.
  • Petro-Sakuma CK, Celino-Brady FT, Breves JP, Seale AP. 2020. Growth hormone regulates intestinal gene expression of nutrient transporters in tilapia (Oreochromis mossambicus). General and Comparative Endocrinology 292: 113464.
  • Breves JP, Starling JA, Popovski CM, Doud JM, Tipsmark CK. 2020. Salinity-dependent expression of ncc2 in opercular epithelium and gill of mummichog (Fundulus heteroclitus). Journal of Comparative Physiology B 190: 219-230.
  • Breves JP. 2020. Hormonal control of aquaporins in fishes. In: Litwack G (Ed.), Vitamins & Hormones  (Vol. 112): Aquaporin Regulation. Academic Press. pp. 265-287.
  • Celino-Brady FT, Petro-Sakuma CK, Breves JP, Lerner DT, Seale AP. 2019. Early-life exposure to 17beta-estradiol and 4-nonylphenol impacts the growth hormone/insulin-like growth-factor system and estrogen receptors in Mozambique tilapia, Oreochromis mossambicus. Aquatic Toxicology 217: 105336.   
  • Seale AP, Pavlosky KK, Celino-Brady FT, Yamaguchi Y, Breves JP, Lerner DT. 2019. Systemic versus tissue-level prolactin signaling in a teleost during a tidal cycle. Journal of Comparative Physiology B 189: 581-594.                   
  • Breves JP. 2019. Prolactin controls branchial clcn2c but not atp1a1a.2 in zebrafish Danio rerio. Journal of Fish Biology 94: 168-172.
  • Breves JP, Duffy TA, Einarsdottir IE, Björnsson BT, McCormick SD. 2018. In vivo effects of 17alpha-ethinylestradiol, 17beta-estradiol and 4-nonylphenol on insulin-like growth-factor binding proteins (igfbps) in Atlantic salmon. Aquatic Toxicology 203: 28-39.
  • Marshall WS, Breves JP, Doohan EM, Tipsmark CK, Kelly SP, Robertson GN, Schulte PM. 2018. claudin-10 isoform expression and cation selectivity change with salinity in salt-secreting epithelia of F. heteroclitus. Journal of Experimental Biology 221: jeb168906.   
  • Yamaguchi Y, Breves JP, Haws MC, Lerner DT, Grau EG, Seale AP. 2018. Acute salinity tolerance and the control of two prolactins and their receptors in the Nile tilapia (Oreochromis niloticus) and Mozambique tilapia (O. mossambicus): a comparative study. General and Comparative Endocrinology 257: 168-176.

    Full List of Publications

Recent Abstracts/Presentations:

  • Breves JP, Puterbaugh KM, Bradley SE, Hageman AE, Verspyck AJ, Shaw LH, Danielson EC, Hou Y. Molecular targets of prolactin signaling in euryhaline mummichogs (Fundulus heteroclitus). 14th International Congress on the Biology of Fish, June 2022, Montpellier, France. 
  • Seale AP, Woo DW, Malintha T, Celino-Brady FT, Yamaguchi Y, Breves JP. Effects of temperature on prolactin release from the tilapia pituitary. 14th International Congress on the Biology of Fish, June 2022, Montpellier, France. 
  • Breves JP. Invited: Prolactin and hydromineral balance in vertebrates: molecular and cellular insights from fishes. FASEB Science Research Conference: The Growth Hormone (GH)/Prolactin (PRL) Family in Biology and Disease, May 2022, Athens, OH.  
  • Bradley SE, Puterbaugh KM, Hageman AE, Verspyck AJ, Shaw LH, Danielson EC, Hou Y, Breves JP. Prolactin directs branchial and intestinal gene expression of solute transporters and aquaporins in mummichog (Fundulus heteroclitus). Experimental Biology, April 2022, Philadelphia, PA.  
  • Breves JP. Invited: Osmoregulatory plasticity in fishes: interplay between environmental conditions and systemic hormones. Experimental Biology, April 2022, Philadelphia, PA.  
  • Celino-Brady FT, Breves JP, Seale AP.Sexually dimorphic responses to growth hormone and luteinizing hormone within the somatotropic and reproductive axes of tilapia. Experimental Biology, April 2022, Philadelphia, PA.  
  • Breves JP. Invited: Salt and water balance in fishes: mechanisms of hormone action. Union College, Department of Biology, March 2022, Schenectady, NY.  
  • Seale AP, Gilman CL, Zavacki AM, Larsen PR, Inokuchi M, Breves JP, Seale LA. The involvement of deiodinases and thyroid hormones during freshwater acclimation in a euryhaline fish. 12th International Symposium on Selenium in Biology and Medicine, February 2022, Honolulu, HI.  
  • Woo DW, Malintha T, Celino-Brady FT, Breves JP, Yamaguchi Y, Seale AP. Thermally induced changes in cell volume and hormone release in prolactin cells of Mozambique tilapia. 6thMeeting of the North American Society for Comparative Endocrinology, May 2021. Virtual.
  • Seale AP, Seale LA, Gilman CL, Zavacki AM, Larsen PR, Inokuchi M, Breves JP. Effects of freshwater acclimation on thyroid hormones and branchial deiodinase in Mozambique tilapia. 6thMeeting of the North American Society for Comparative Endocrinology, May 2021. Virtual.
  • Celino-Brady FT, Breves JP, Seale AP. Sex-dependent modulation of genes involved in growth and reproduction by growth hormone and luteinizing hormone in tilapia. 6thMeeting of the North American Society for Comparative Endocrinology, May 2021. Virtual. 
  • Breves JP. Invited: Endocrine perspectives on the growth of Atlantic salmon: effects of nutrition, stress, and endocrine disruptors. University of Hawaii SeaGrant, January 2020, Honolulu, HI. 
  • Breves JP. Invited: Molecular endocrinology of hydromineral balance in fishes. University of Buffalo, Department of Biological Sciences, October 2019, Buffalo, NY. 
  • Breves JP. Plenary: Prolactin supports ion uptake by teleost ionocytes. North American Society for Comparative Endocrinology, May 2019, Gainesville, FL.
  • Chang AY, Kalinowski MC, McCormick SD, Kelly JT, Breves JP. Does the synthetic corticosteroid, prednisolone, impact the insulin-like growth-factor binding protein (igfbp) network of Atlantic salmon parr? Experimental Biology, April 2019, Orlando, FL.
  • White RL, Cairnduff RF, Nilsen TO, Einarsdottir IE, Björnsson BT, McCormick SD, Breves JP. Effects of adrenosterone, testosterone, and 17beta-estradiol on the gene expression of insulin-like growth-factor binding proteins (igfbps) in Atlantic salmon smolts. Experimental Biology, April 2019, Orlando, FL.
  • Breves JP, Duffy TA, Springer-Miller RH, Chenoweth DA, Paskavitz AL, Regish AM, Einarsdottir IE, Björnsson BT, McCormick SD. Cortisol and estrogenic compounds modulate insulin-like growth-factor binding protein gene expression during vulnerable life stages of Atlantic salmon. Intersociety Meeting: Comparative Physiology, American Physiological Society, October 2018, New Orleans, LA.
  • Breves JP. Plenary: Hormonal control of teleost ionocytes: mechanisms of prolactin action. 13th International Congress on the Biology of Fish, American Fisheries Society, July 2018, Calgary, Canada.

Selected Awards:

  • New Investigator Award; American Physiological Society, Comparative and Evolutionary Physiology Section (2019)
  • Gorbman-Bern New Independent Investigator Award; North American Society of Comparative Endocrinology (2019)
  • Scholander Award; American Physiological Society, Comparative and Evolutionary Physiology Section (2013)
  • Research Recognition Award; American Physiological Society, Comparative and Evolutionary Physiology Section (2013)
  • Ruth L. Kirschstein National Research Service Awards (T32/F32), National Institutes of Health, NIMH & NIDDK (2011-2013)

Memberships:

  • American Physiological Society (APS)
  • North American Society for Comparative Endocrinology (NASCE)
  • Society for Integrative and Comparative Biology (SICB)
  • Center for Neuroendocrine Studies (CNS), UMass Amherst
  • Sigma Xi