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Skidmore College
Biology Department

David DomozychDavid Domozych

Professor of Biology and
Director of the Skidmore Microscopy Imaging Center

Dana Science Center, Office #343
Biology Department
Saratoga Springs, NY  12866
Telephone: 518-580-5075
Fax: 518-580-5071

Other Positions Held:

  • 2011, Visiting Scientist, National University of Ireland, Galway.
  • 1989-1990, Visiting Scientist, John Innes Institute, Norwich England.
  • 1997-1998, Visiting Professor, Section of Plant Biology, Cornell University.

Courses Taught at Skidmore:

  • Molecular and Cellular Foundations of Life (BI 107)
  • Plant Biology (BI 237)
  • Biological Electron Microscopy (BI 311)
  • Plant Biochemistry and Physiology (BI 337)
  • Plant Biotechnology (BI 338)
  • Advanced Light Microscopy (BI 362)

Research Interests:

David Domozych is a plant cell biologist who studies the evolution of cell walls and their biosynthesis in plants. He is interested in the biochemistry and cell biology of cell wall polymers and other components of the extracellular matrix of the basal Streptophyta or charophytes, i.e., the extant group of green algae whose ancestors are the basal stock from which land plants evolved. Dr. Domozych's primary research tools include light, microscopy, confocal laser scanning microscopy and electron microscopy, immunocytochemistry, and multiple biochemical methodologies. His main subject of study is the model unicellular streptophyte, Penium margaritaceum. Currently, his research work is involved in answering questions such as:

  • How do different cell wall polymers function during cell development? How do pectins and arabinogalactan proteins of the cell wall interact during cell expansion?
  • How are various wall polymers processed in the plant Golgi Apparatus, packaged in specific vesicle types and transported to the cell surface? What are the molecular controls and signal transduction components of plant cell wall synthesis and secretion?
  • What are the extracellular polymeric substances (EPS) of streptophyte algae? How are they produced and what are their functions?

He is also interested in the structural architecture and biosynthesis of the extracellular matrix of tomatoes, the development of root hairs in Arabidopsis and the molecular components/dynamics of the endomembrane system and secretory apparatus of plants.

Dr. Domozych's work has recently been sponsored by grants from the National Science Foundation's (NSF) Molecular and Cell Biology Program, NSF Integrated Organismal Systems and NSF Major Instrumentation Programs. Many students participate in his research program both during the academic year and summer.

Recent Publications:

  • Domozych, D.S., Sun, L., Palacio-Lopez, K., Reed, R., Jeon, S., Li, M., Jiao, C., Sørensen, I., Fei, Z. and Rose, J.K.C. (2020) Endomembrane architecture and dynamics during secretion of the extracellular matrix of the unicellular charophyte, Penium margaritaceum, Journal of Experimental Botany:
  • Jiao, C., Sørensen, I., Sun, X., Behar, H., Alseekh, S., Philippe, G., Fernie, A.R., Brumer, H., Domozych, D.S., Fei, Z. and Rose, J.K.C. (2020) The Genome of the Charophyte Alga Penium margaritaceum Bears Footprints of Terrestrialization and Preludes the Evolutionary Origins of Land Plants, Cell 181: 1-15.,

  • Philippe, G., Sørensen, I., Jiao, C., Sun, X.,  Fei, Z., Domozych, D.S. and Rose, J.K.C. (2020) Cutin and suberin: assembly and origins of specialized lipidic cell wall scaffolds. Current Opinion in Plant Biology 55: 11-20.
  • Palacio-Lopez, K.,  Tinaz, B., Holzinger, A. and Domozych, D.S. (2019) Arabinogalactan Proteins and the Extracellular Matrix of Charophytes: A Sticky Business. Frontiers in Plant Science
  • Rodriguez-Furlan, C., Domozych, D., Qian, W., Enquist, P.A.,  Li, X., Zhang, C., Schenk, R., Saulsbery Winbigler, H., Jackson, W., Raikhel, N.V. and Hicks, G.R. (2019) Interaction between VPS35 and RABG3f is necessary as a checkpoint to control fusion of late compartments with the vacuole. Proceedings of the National Academy of Sciences 116: 21291-21301.
  • Wilkop, T., Pattathil, S., Ren, G., Davis, D.J., Bao, W., Duan, D., Peralta, A.G., Domozych, D.S., Hahn, M.J. and. (2019) A Hybrid Approach Enabling Large-Scale Glycomic Analysis of Post-Golgi Vesicles Reveals a Transport Route for Polysaccharides. Plant Physiology 31: 627-641.

  • Rosquette, M.R., Worden, N., Ren, G., Sinclair, R.M., Pfleger S., Salemi, M., Phinney, B.S., Domozych, D., Wilkop, T. Drakakaki. G. (2019) AtTRAPPC11/ROG2: A Role for TRAPPs in Maintenance of the Plant Trans-Golgi Network/Early Endosome Organization and Function. Plant Cell 31: 1879-1898. 

  • Shinozaki, Y., Nichols, P., Fernandez-Pozo, N., Ma, Q., Evanich, D.J., Shi, Y., Xu, Y., Zheng, Y., Snyder, S.I., Martin, L.B.B., Ruiz-May, E., Thannhauser, T.W., Chen, K., Domozych, D.S., Catalá, C., Fei, Z., Mueller, L., Giovannoni, J.J. and Rose, J.K.C. (2018) High-resolution spatiotemporal transcriptome mapping of tomato fruit development and ripening. Nature Communications 9: 364.

  • Raimundo, S.C., Sørensen, I., Tinaz, B., Ritter, E., Rose, J.K.C., and Domozych, D.S. (2018) Protoplast isolation and manipulation of protoplasts from the unicellular green alga Penium margaritaceumPlant Methods 14: 18.
  • Martin, L.B.B., Romero, P., Fich, E.A., Domozych, D.S., and Rose, J.K.C. (2017) Cuticle Biosynthesis in Tomato Leaves is Developmentally Regulated by Abscisic Acid. Plant Physiology 174: 1384-1398.

  • Mravec, J., Kračun, S.K., Rydahl, M.G., Westereng, B., Pontiggia, D., De Lorenzo, G., Domozych, D.S. and Willats, W.G.T. (2017) An oligogalacturonide-derived molecular probe demonstrates the dynamics of calcium-mediated pectin complexation in cell walls of tip-growing structures. The Plant Journal 91: 534-546.
  • Mravec, J., Guo, X., Hansen, A.R., Schückel, J., Kračun, S.K., Mikkelsen, M.D., Mouille, G., Johansen, E., Ulvskov, P., Domozych, D.S., and Willats, W.G.T.  (2017) Pea Border Cell Maturation and Release Involve Complex Cell Wall Structural Dynamics. Plant Physiology 174: 1051-1066. 
  • Tafolla-Arellano, J.C., Zheng, Y., Sun, H., Jiao, C., Ruiz-May, E., Hernández-Oñate, M.A., González-León, A., Báez-Sañudo, R., Fei, Z., Domozych, D., Rose, J.K.C., and Tiznado-Hernández, M.E. (2017) Transcriptome Analysis of Mango (Mangifera indica L.) Fruit Epidermal Peel to Identify Putative Cuticle-Associated Genes. Scientific Reports 7: 46163.

  • Uluisik, S., Chapman, N.H., Smith, R., Poole, M., Adams, G., Gillis, R.B., Besong, T.M.D., Sheldon, J., Stiegelmeyer, S., Perez, L., Samsulrizal, N., Wang, D., Fisk, I.D., Yang, N., Baxter, C., Rickett, D., Fray, R., Blanco-Ulate, B., Powell, A.L.T., Harding, S.E., Craigon, J., Rose, J.K.C., Fich, E.A., Sun, L., Domozych, D.S., Fraser, P.D., Tucker, G.A., Grierson, D., and Seymour, G.B. (2016) Genetic improvement of tomato by targeted control of fruit softening. Nature Biotechnology 34: 950-952.

Visit us here for a complete list of additional publications.

Grants received:-Last 5 years

  • NSF MRI 1828508: Acquisition of a Field Emission Scanning Electron Microscope and Energy Dispersive Spectrometry Attachment for High Resolution Imaging at Skidmore College; 10/01/2018- 9/30/2022; $621,026

  • NSF MCB 1517345: Collaborative Research: Invasion of land: Using model charophyte Penium margaritaceum to elucidate subcellular responses to stress that were key in the evolution of land plants. 07/15/2015-03/15/2019; $382,669.
  • NSF MRI 1337280: Acquisition of a confocal laser scanning microscope for research in the life sciences at Skidmore College; 09/01/2013-08/31/2016; $478,730.00.
  • NSF MCB 1009978: The cell biology of pectin dynamics in the Charophycean Green Algae: Homogalacturonan secretion in the model organism, Penium margaritaceum; 02/10/2010-09/30/2012; $232,000.
  • NSF MRI 0922805: MRI: Acquisition of a Libra 120 transmission electron microscope for research enhancement at Skidmore College. 01/01/2010- 12/31/2013; $721,046.00.
  • NSF MRI 0959476: MRI-R2: From Molecules to Ecosystems: Establishment of the Skidmore Analytical Interdisciplinary Laboratory (SAIL); 01/01/2010- 12/31/2014; $557,755.00.

Research Collaborators from around the world:

  • Dr. Zoe Popper, National University of Ireland
  • Drs. Jocelyn Rose and Iben Sorensen, Cornell University
  • Dr. William Willats, University of Newcastle
  • Dr, Georgia Drakakaki, University of California at Davis
  • Dr. Mary Tierney, University of Vermont