Skip to Main Content
Skidmore College

Skidmore team earns patent for use of antioxidant compound

December 10, 2013

Skidmore team earns patent for use of antioxidant compound

Dec. 10, 2013

Jonathan Brestoff Parker ’08
Jonathan Brestoff Parker ’08

A Skidmore alumnus and professor have been awarded U.S. Patent No. 8,598,150 for use of an antioxidant compound that shows promise in the treatment of obesity and related disorders, such as type-2 diabetes.

The researchers—Jonathan R. Brestoff Parker, a 2008 graduate who is currently a trustee of the College, and Thomas H. Reynolds, associate professor of health and exercise sciences—discovered that treating obese mice with an antioxidant called MnTBAP* decreases obesity and improves type-2 diabetes.

T.H. Reynolds
T.H. Reynolds

Obese mice that received the compound lost 40 percent of their body weight. “To put that number in context, if a 300-pound obese person lost 40 percent of their body weight, they would have lost 120 pounds,” said Brestoff Parker.

The compound works by breaking down triglycerides, which are stored in excess in fat tissue of obese people. The researchers’ next step, according to Reynolds, is “to figure out how that happens. What are the cellular and molecular events that result in weight loss?” He calls this stage of drug development “the fun part of science—trying to design the next study that will yield information about how a biological system responds to a drug.”

Related News


Sarah+Friedland%2C+Storytellers%27+Institute+Director+solders+during+an+open+house+at+The+Hub
Students, staff and faculty joined together for an afternoon of mystery “making” at the Hub, a Skidmore maker space.
Apr 19 2018

Skidmore News
The contract for the construction of the first phase of Center for Integrated Sciences (CIS) has been awarded to MLB Construction Services of Malta, New York. The firm also managed the construction of the Hillside apartments, Sussman Village and the Arthur Zankel Music Center.
Apr 19 2018

Professor+Sheldon+Solomon+teaching+his+Scribner+Seminar%2C+Human+Dilemmas
Inspired by Skidmore professors’ intellectual curiosities and passions, the Scribner Seminar is a cornerstone of the First-Year Experience. Browse a few of the Fall 2018 seminar offerings.
Apr 18 2018