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Skidmore College
Chemistry Department


Recent Publications by Skidmore Chemistry Faculty


(Skidmore Chemistry faculty in bold, Skidmore undergraduates underlined)


C. A. Vilchis-Nestor, M. L. Roldán, A. Leonardi, J. G. Navea, T. Padilla-Benavides, L. Shoshani. Ouabain enhances cell-cell adhesion mediated by β1 subunits of the Na+,K+-ATPase in CHO fibroblasts. Int. J. Molec. Sci. 2019. 20(9), 2111.

J. V. G. Shellaina, Y. Xiao, A. L. Paskavitz, N. Navarro-Tito, J. G. Navea, T. Padilla-Benavides. Atomic absorbance spectroscopy as a tool to measure intracellular Zn pools in mammalian cells. Journal of Visualized Experiments. 2019. (147), e59519. Authors contributed equally to the work. 

Ball, K. AureliaChan, L. M., Stanley, D. J., Tierney, E., Thapa, S., Ta, H. M., Burton, L., Binning, J. M., Jacobson, M. P., Gross, J. D. (2019). Conformational Dynamics of the HIV-Vif Protein Complex. Biophysical Journal, 116(8), 1432-1445.

Roca, M., Skipper, H. E., Ndrianasy, J. R.(2019). Optical Properties of Nanocomposite Films: Size-tuned vs. Shape-tuned Silver Nanoparticles. American Journal of Nanomaterials, 7(1), 22-29.

Matias, A., Dudar, M., Kauzlaric, J., Frederick, K., Fitzpatrick, S., Ives, S. (2019). Rehydrating efficacy of maple water after exercise-induced dehydration. Journal of the International Society of Sports Nutrition, 16(1), 5.


Navea's JPCA cover artOstaszewski, C. J.;Stuart, N. M.;  Lesko, D. M. B.;  Kim, D.; Lueckheide, M. J.; Navea, J. G., Effects of Coadsorbed Water on the Heterogeneous Photochemistry of Nitrates Adsorbed on TiO2. Phys. Chem. A 2018,122(31), 6360-6371.



Navea, J. G.;Grassian, V. H.; Wandelt, K., Photochemistry of Atmospheric Particles. In Encyclopedia of Interfacial Chemistry, Elsevier: Oxford, 2018; pp 553-562.

Narum, J.;Frederick, K.; Pallafino, M., 21st Century Spaces for 21st Century Learners: Where We Are, How We Got Here, and What Next. Scholarship and Practice of Undergraduate Research 2018,1(3), 12-17.

Frey, S. T.;Li, J.;  Kaur, M.; Jasinski, J. P., Crystal structure of a mononuclear copper(II) complex with 2-methoxy-N,N-bis(quinolin-2-ylmethyl)ethylamine (DQMEA). Acta Crystallogr., Sect. E Crystallogr. Commun. 2018,74(8), 1138-1141.

Frey, S. T.;Ramirez, H. A.;  Kaur, M.; Jasinski, J. P., Crystal structure of a seven-coordinate manganese(II) complex with tris(pyridin-2-ylmethyl)amine (TMPA). Acta Crystallogr., Sect. E Crystallogr. Commun. 2018,74(8), 1075-1078.

Roca, M., Is It a Meteorite? Applying Problem-Solving Strategy to Mass Spectra and Atomic Mass. In National Center for case study teaching in science, University at Buffalo: Buffalo, NY, 2018.

Paskavitz, A. L.; Quintana, J.; Cangussu, D.;  Tavera-Montanez, C.;  Xiao, Y.;  Ortiz-Miranda, S.;  Navea, J. G.; Padilla-Benavides, T., Differential expression of zinc transporters accompanies the differentiation of C2C12 myoblasts. Trace Elem. Med. Biol. 2018,49, 27-34.

Silva, W. Ruchira, Hart, S., Frontiera, R. (2018). Femtosecond stimulated Raman evidence for charge-transfer character in pentacene singlet fission. Chemical Science, 9, 1242-1250.


Keller, V. A.; Kendall, B. L., Independent Synthesis Projects in the Organic Chemistry Teaching Laboratories: Bridging the Gap Between Student and Researcher. J. Chem. Educ. 2017,94(10), 1450-1457. DOI: 10.1021/acs.jchemed.7b00093

Navea JG, Richmond E, Stortini T, Greenspan J. Water adsorption isotherms on fly ash from several sources. Langmuir. 2017. DOI: 10.1021/acs.langmuir.7b02028

Ferro A, Carbone E, Marzouk E, Siegel A, Nguyen D, Polley K, Hartman J, Frederick KIves, S., and Lagalwar S et al. (2017) Treating SCA1 Mice with Water-Soluble Compounds to Non-Specifically Boost Mitochondrial Function. J. Vis. Exp. (119), e53758.

Ferro, A.;Carbone, E.;  Zhang, J.;  Marzouk, E.; Villegas, M.;  Siegel, A.;  Nguyen, D.; Possidente, T.;  Hartman, J.;  Polley, K.; Ingram, M. A.;  Berry, G.;  Reynolds, T. H.;  Possidente, B.;  Frederick, K.;  Ives, S.; Lagalwar, S., Short-term succinic acid treatment mitigates cerebellar mitochondrial OXPHOS dysfunction, neurodegeneration and ataxia in a Purkinje-specific spinocerebellar ataxia type 1 (SCA1) mouse model. PLoS One 2017,12(12), e0188425/1-e0188425/20.


Ball KA, Johnson JR,  Lewinski MK, Guatelli J, Verschueren E, Krogan NJ, Jacobson MP (2016). Non-Degradative Ubiquitination of Protein Kinases. PLoS Computational Biology, 12, e1004898.

Borgatta J, Paskavitz A, Kim D, Navea JG (2016) Comparative evaluation of iron leach from different sources of fly ash under atmospherically relevant conditions. Environ. Chem. 2016, 13(5) 902-912.

Heusser SA, Yoluk, Klement G, Riederer EA, Lindahl E, Howard RJ (2016) Functional characterization of neurotransmitter activation and modulation in a nematode model ligand-gated ion channel. J. Neurochem.DOI: 10.1111/jnc.13644.

Nair N, Raff H, Islam MT, Feen M, Garofalo DM, Sheppard K (2016) The Bacillus subtilis and Bacillus halodurans aspartyl-tRNA synthetases retain recognition of tRNAAsn. J. Mol. Biol., 428, 618-630.


Lesko DMB, Coddens EM, Swomley HD, Welch RM, Borgatta J, Navea JG (2015) Photochemistry of nitrate chemisorbed on various metal oxide surfaces. Physical Chem. Chemical Physics 17, 20775-20785.

Suhanovsky MH, Sheppard K, Rowlett RS (2015) Beta-carbonic anhydrases: general features and medical implications. In De Simone, G., and Supuran, C.T. (eds.) Carbonic Anhydrases as Biocatalysts: from Theory to Medical to Industrial Applications, Elsevier, Amsterdam, The Netherlands, Oxford, UK, Waltham, MA, pp. 247-273.

Horani S, Stater EP, Corringer P-J, Trudell JR, Harris RA, Howard RJ (2015) Ethanol modulation is quantitatively determined by the transmembrane domain of human α1 glycine receptors. Alcoholism: Clinical & Experimental Research 39, 962 – 968.

Ancutiene I, Navea JG, Baltrusaitis J (2015) Surface structural, chemical and optical properties of polyethylene-copper sulfide composite materials synthesized using sorption-diffusion of polythionic acid.  Appl. Surf. Sci. 347, 520–527.

Borgatta J, Navea JG (2015) Fate of aqueous iron leached from tropospheric aerosols during atmospheric acidic processing: a study of the effect of humic-like substances. WIT Trans. Ecol. Environ. 198, 155-166.

Suzuki T, Nakamura A, Kato K, Söll D, Tanaka I, Sheppard K, Yao M (2015) Structure of the Pseudomonas aeruginosa transamidosome reveals unique aspects of bacterial tRNA-dependent asparagine biosynthesis. Proc. Nat. Acad. Sci. 112, 382-387.


 Alperstein A, Ulrich B, Garofalo DM, Dreisbach R, Raff H, Sheppard K (2014) The predatory bacterium Bdellovibrio bacteriovorus aspartyl-tRNA synthetase recognizes tRNAAsn as a substrate. PLoS ONE 9(10): e110842.

 Howard RJ, Trudell JR, Harris RA. (2014) Seeking structural specificity: direct modulation of pentameric ligand-gated ion channels by alcohols and general anesthetics. Pharmacol. Rev. 66, 396-412.

Halstead JA, Kliman S, Berheide CW, Chaucer A, Cock-Esteb A (2014) Urban stream syndrome in a small, lightly developed watershed: a statistical analysis of water chemistry parameters, land use patterns, and natural sources. Envir. Mont. Assess. 186, 3391-3414.

 Mladenova SR, Stein KR, Bartlett L, Sheppard K (2014) Relaxed tRNA specificity of the Staphylococcus aureus aspartyl-tRNA synthetase enables RNA- dependent asparagine biosynthesis. FEBS Lett. 588, 1808-1812.


Frederick KA (2013) The Joys and Pitfalls of Collaboration in the Research Process, in How to Get Started in Research ed. M. Schuh, Council on Undergraduate Research, Washington, DC, 54-57

Frederick KA (2013) Using forensic science to teach method development in the undergraduate analytical laboratory. Anal. Bioanl. Chem. 405, 5623-5626.

Heusser SA, Howard RJ, Borghese CM, Cullins MA, Broemstrup T, Lee US, Lindahl E, Carlsson J, Harris RA (2013) Functional validation of virtual screening for novel agents with general anesthetic action at ligand-gated ion channels. Mol. Pharmacol. 84, 670-8.

Brömstrup T, Howard RJ, Trudell JR, Harris RA, Lindahl E (2013) Inhibition versus potentiation of ligand-gated ion channels can be altered by a single mutation that moves ligands between intra- and intersubunit sites. Structure 21, 1307-16.

Halstead JA (2013) Teaching the Spin Selection Rule: An Inductive Approach. J. Chem. Educ. 90, 70-75.

Sauguet L, Howard RJ, Malherbe L, Lee US, Corringer P-J, Harris RA, Delarue M (2013) Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel. Nature Commun. 4 1697.

Spurny R, Billen B, Howard RJ, Brams M, Debaveye S, Price K, Weston D, Strelkov S, Tytgat J, Bertrand S, Bertrand D, Lummis S, Ulens C (2013) Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia crysanthemiligand-gated ion channel (ELIC). J Biol Chem 288, 8355–64.


Fidopiastic PM, Rader BA, Gerling DG, Gutierrez NA, Watkins KH, Frey MW, Nyholm SV, Whistler CA (2012) Characterization of a Vibrio fischeri Aminopeptidase and Evidence for Its Influence on an Early Stage of Squid Colonization. J. Bacter. 194, 3995-4002.

Frederick KA (2012) CUR and NCUR Join Forces on Undergraduate Research. J. Chem. Ed. 89, 183-184.

Wenzel TJ, Larive CK, Frederick KA (2012) Role of Undergraduate Research in an Excellent and Rigorous Undergraduate Chemistry Curriculum. J. Chem. Ed. 89, 7-9.

Kennerly WW, Billings KB, Geragotelis AD, O’Donnell JL (2012) A Computational Approach to Walsh Correlation Diagrams for the Inorganic Chemistry Curriculum. Chem. Educator 17, 57-63.

Swords KE, Bartline PB, Roguski KM, Bashaw SA, Frederick KA (2011) Assessment of polyelectrolyte coating stability under dynamic buffer conditions in CE. J. Sep. Sci. 34, 2427-2432.


O’Donoghue P, Sheppard K, Nureki O, Söll D (2011) Rational design of an evolutionary precursor of glutaminyl-tRNA synthetase. Proc. Natl. Acad. Sci. U.S.A. 108, 20485-20490.

Iimoto DS, Frederick KA (2011) Incorporating Student-Designed Research Projects in the Chemistry Curriculum. J. Chem. Ed. 88, 1069-1073.

Fenton OS, Tonge LA, Moot TH, Frederick KA (2011) Quantitative Analysis of Simulated Illicit Street-Drug Samples Using Raman Spectroscopy and Partial Least Squares Regression. Spect. Lett. 44, 229-234.

Englert M, Sheppard K, Aslanian A, Yates III J, Söll D (2011) Archaeal 3'-phosphate RNA splicing ligase characterization identifies the missing component in tRNA maturation. Proc. Natl. Acad. Sci. U.S.A. 108, 1290-1295.


Englert M, Sheppard K, Gundllapalli S, Beier H, Söll D (2010) Branchiostoma floridae has separate healing and sealing enzymes for 5′-phosphate RNA ligation. Proc. Natl. Acad. Sci. U.S.A. 107, 16834-16839.

Fox KM, Berheide CW, Frederick KA, Johnson B (2010) Adapting Mentoring Programs to the Liberal Arts College Environment, in Mentoring Strategies To Facilitate the Advancement of Women Faculty; Karukstis, K., et al.;ACS Symposium Series; American Chemical Society: Washington, DC, 27-41.

Frey MW, Frey ST, Soltau SR (2010) Exploring the pH Dependence of L-leucine-p-nitroanilide Cleavage by Aminopeptidase AeromonasProteolytica: A Combined Buffer-Enzyme Kinetics Experiment for the General Chemistry Laboratory. Chem. Educator 15, 117-120.

Halstead JA (2010) The Waters Gather: Comments on the Source of the Hudson, in Ian Berry and Tom Lewis ed., Lives of the Hudson, Prestel Publishing, New York, 28-35.

Frey ST, Gullmet SL, Egan III RG, Bennett A, Soltau SR, Holz RC (2010) Immobilization of the Aminopeptidase from Aeromonas proteolytica on Mg2+/Al3+ Layered Double Hydroxide Particles. Appl. Mater. Interfaces 2, 2828-2832