Bernard P. Possidente
Professor of Biology @ Skidmore since 1983
Dana Science Center Room 317
Department of Biology
Saratoga Springs, New York 12866
B.A., Wesleyan University
Ph.D., University of Iowa
Postdoctorate, Florida State University
Advanced Topics in Genetics (BI 352)
Genetics (BI 245)
Biological Clocks (BI 344)
Genes and Generation (SSP-008 First Year Seminar)
Human Genetics (BI 170)
of Alzheimer's Disease"
University, UK Department of Genetics,who made transgenic fly lines
with copies of mutant human genes associated with Alzheimer's.
Dr. Possidente's general research area is genetic analysis of behavioral mechanisms. His research focuses on the function of biological clocks in controlling circadian (daily-endogenous) rhythms using mice and fruitflies as model systems: manipulation of rhythms in mice and fruitflies with genetic, pharmacological, and photoperiod treatments inorder to identify functional properties of circadian system components and their physiological mechanisms.
Recent Publications: (*Indicates student co-author)
Kohiyama M*, Bonser D, Leung L*, Fall A*, Canada N*, Qu B, Ahmad S, Possidente B (2018) The Drosophila apterous56f mutation impairs circadian locomotor activity. Biol Rhythm Res, 46:275-285
Sheppard A, Hirsch HVB, Possidente B, (2015) Novel Masking Effects of Light Are Revealed in Drosophila by Skeleton Photoperiods. Biological Rhythms Research, 46 (2) 275-285.
Chen K-F, Possidente B, Lomas DA, Crowther DC (2014) The Central Molecular Clock Is Robust in the Face of Behavioural Arrhythmia in a Fly Model of Alzheimer’s Disease. Disease Models and Mechanisms (Open Access http://dmm.biologists.org/), doi:10.1242/dmm.014134.
Possidente, B. (2013) Rhythms and Sleep: Circadian and Seasonal Activity Patterns. In: Crusio WE, Sluyter F, Gerlai RT and S. Pietropaolo (eds.) Volume 1, Genetics of Behavioral Phenotypes: Cambridge Handbooks in Behavioral Genetics Series. Cambridge University Press, Cambridge, UK, pages 128-147.
Ahmad ST, Steinmetz SB, Bussey HM, Possidente B, Seggio JA. (2013) Larval Ethanol Exposure Alters Free-running Circadian Rhythm and per Locus Transcription in Adult D. melanogaster period Mutants. Behav Brain Res. 241:50-55
Hagenauer MH, King AF, Possidente B, McGinnis MY, Lumia AR,Lee TM. (2010) Changes in Circadian Rhythms During Puberty in Rattus Norvegicus: Developmental time course and gonadal dependency. Hormones and Behavior, 60(1):46-57.
Ruden DM, Chem L, Rasouli P, Wang L, Lu X, Garfinkel MD, Possidente D, Possidente B, Hirsch HVB, Page GP (2009) Genetical toxicogenomics in Drosophila identifies master modulatory loci that are regualted by developmental exposure to lead. NeuroToxicology, 30:898-914.
Hirsch HVB, Possidente D, Averill S, Despain J, Buytkins J, Thomas V, Goebel P, Shipp-Hilts A, Hollocher K, Wilson D, Possidente B and D Rudin (2009) Behavioral QTL after Developmental Exposure of Drosophila melanogaster to Lead. NeuroToxicology 30:305-311
Possidente, B. (2007) Genetics and The Sopranos. Letters, Science 317:596.
Possidente, B. (2007) Genetic Dialogs in The Sopranos in Six Parts. Science Creative Quarterly;http://www.scq.ubc.ca/ Issue 3, Commentary. September 7th-April 8th.